Dermaworks Retinol Serum with hyaluronic acid, vitamin E, and jojoba oil—anti-aging face serum for fine lines, wrinkles, and skin renewal, shown in sleek bottle with packaging.

2.5% Retinol Night Serum | High Strength Anti-Ageing

£ 14.95 GBP
£ 14.95 GBP
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Dermaworks Retinol Serum with hyaluronic acid, vitamin E, and jojoba oil—anti-aging face serum for fine lines, wrinkles, and skin renewal, shown in sleek bottle with packaging.
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2.5% Retinol Night Serum | High Strength Anti-Ageing

97 reviews

2.5% Retinol Night Serum | High Strength Anti-Ageing

The Holy Grail of anti-aging ingredients!

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Vegan • Cruelty-Free • 72% Organic
Free UK shipping over £30

Wake up to visibly smoother, firmer skin. Our High Strength Retinol Night Serum is a clinically formulated, dermatologist-tested treatment that works while you sleep — accelerating cell renewal, stimulating collagen production, and reducing the appearance of fine lines and wrinkles from the very first weeks of use.

Cruelty-free. Vegan. Professional-grade. Made for results.

Key Benefits

  • Visibly reduces fine lines & wrinkles — high-strength retinol stimulates collagen for firmer, plumper skin
  • Accelerates cell renewal — resurfaces dull, uneven skin texture overnight
  • Improves skin tone & clarity — fades dark spots and pigmentation with consistent use
  • Dermatologist-tested formula — professional-grade actives, developed for sensitive skin compatibility
  • Cruelty-free & vegan — no compromise on ethics or efficacy

How to Use

Apply 2–3 drops to clean, dry skin each evening. Begin with 2–3 nights per week, increasing frequency as your skin builds tolerance. Always apply SPF the following morning — retinol increases photosensitivity.

For best results, use consistently for 8–12 weeks.
Ingredients

Witch Hazel, Glycerin, Organic Aloe Vera Extract, Retinol, Organic Green Tea Extract, Organic Gotu Kola, Proplis Extract, Botanical Hyaluronic Acid, Ethylhexglycerin, Horsetail Extract, Dandelion Extract, Wild Geranium Extract, Vitamin E, Sodium Benzoate, Potassium Sorbate, Wheat Germ Oil, Organic Jojoba Oil, Ethylcellulose, Carrageenan Gum.
Shipping

Delivery information - all products

UK, CHANNEL ISLES & ISLE OF MAN

Orders over £30:

  • FREE standard delivery (3-5 working days)
  • £1.99 express delivery (1-2 working days)

Orders under £30:

  • £3.49 standard delivery (3-5 working days)
  • £4.99 express delivery (1-2 working days)

EUROPE — £12.95 flat fee (5-10 working days)
VAT included at checkout via IOSS — no surprise charges on delivery.

USA — £14.95 singles / £22.95 bundles & sets (5-10 working days)
Duties and taxes included — nothing extra to pay on delivery.

REST OF THE WORLD — £16.95 flat fee (7-10 working days)
Import duties and taxes may apply on arrival.

All orders dispatched Monday–Friday. Same day dispatch on orders placed before 3:00pm. All orders sent using a tracked delivery service.

We ship to selected countries. Contact us if your country isn't available at checkout.

60-DAY MONEY-BACK GUARANTEE
Not happy? Return any product within 60 days for a full refund — even if opened. Return postage is at the customer's cost. Full returns policy →
Money Back Guarantee

We keep our money back guarantee simple because we believe in our products : If you have used our product every day for 30 days and you do not see noticeable results, we will give you your money back. Just drop us an email to let us know and we will arrange your refund, no fuss, no hassle. Money back guarantee claims become eligible 30 days from the date of delivery. Only one refund per household is permitted. Customer pays for return postage.

As Seen In

Dermaworks vegan high quality cruelty free skincare beauty eyebrow and eyelash growth serums as seen in British Vogue Magazine
Dermaworks vegan high quality cruelty free skincare beauty eyebrow and eyelash growth serums as seen in Tatler Magazine
dermaworks advanced daily pro collagen moisturiser for women pure radiance face cream for ladies as featured in the Cheshire magazine
dermaworks triple serum gift set box complete skincare bundle for women as seen on ideal world
dermaworks retinol anti aging collagen stimulating face serum for women youthful radiant firmer plum hydrated face skin as seen in health & wellbeing magazine
the daily express newspaper featuring dermaworks hydrating hyaluronic acid face serum with aloe vera powerful natural skin plumping for women over 50
Dermaworks vegan high quality cruelty free skincare beauty eyebrow and eyelash growth serums as seen in British Vogue Magazine
Dermaworks vegan high quality cruelty free skincare beauty eyebrow and eyelash growth serums as seen in Tatler Magazine
dermaworks advanced daily pro collagen moisturiser for women pure radiance face cream for ladies as featured in the Cheshire magazine
dermaworks triple serum gift set box complete skincare bundle for women as seen on ideal world
dermaworks retinol anti aging collagen stimulating face serum for women youthful radiant firmer plum hydrated face skin as seen in health & wellbeing magazine
the daily express newspaper featuring dermaworks hydrating hyaluronic acid face serum with aloe vera powerful natural skin plumping for women over 50
"I noticed my skin cleared up almost immediately with this product. I actually think it's magic. It's also great value for money because you only need about 3 drops to cover your entire face - so it will last & last!"

Helli Rose

Rejuvenate your skin with our anti-wrinkle, pore minimizer serum that boosts collagen and helps fade dark spots.

Why you need to add Retinol to your skincare routine

Adding retinol to your skincare routine is one of the most effective ways to fight signs of aging and improve overall skin texture. Retinol speeds up cell turnover, helping to fade dark spots, smooth fine lines, and clear clogged pores. It supports collagen production, keeping your skin firm and youthful over time. Whether you want to target wrinkles, acne, or dullness, a quality retinol serum delivers visible, lasting results. It’s a powerhouse ingredient that transforms your skin from tired to radiant with consistent use.

How to add Retinol to your routine

1

Begin by applying your retinol serum 2–3 times a week at night to allow your skin to adjust. Gradually increase frequency as your skin builds tolerance.

2

On clean, dry skin, use a pea-sized amount of retinol. Gently smooth it over your face, avoiding the eye and lip areas.

3

Follow with a nourishing moisturiser to keep skin hydrated, and always use suncream during the day — retinol makes your skin more sensitive to UV rays.

When layering serums, apply your hydrating or soothing serums before retinol (like hyaluronic acid) and save vitamin C for the morning. This helps minimise irritation and keeps your skin balanced and glowing.

What makes this serum work?

Retinol

Retinol

boosts cell turnover, smooths fine lines, fades dark spots, and stimulates collagen production

Organic green tea extract

Organic green tea extract

soothes irritation, fights free radicals, and helps reduce redness

hyaluronic acid

hyaluronic acid

Boosts hydration

Organic jojoba oil

Organic jojoba oil

powerhouse multitasker for the skin — lightweight, balancing, and deeply nourishing.

Vitamin E

Vitamin E

Lock in moisture, repair damage, and promote a smooth, healthy glow.

Organic aloe vera extract

Organic aloe vera extract

Soothes and calms sensitive skin

Frequently asked questions
How do I use retinol safely?

Start Slowly: Begin with 2-3 times per week to allow your skin to adjust. Gradually increase frequency as your skin builds tolerance.

Always Use SPF: Retinol increases sun sensitivity. Apply SPF 30+ daily during the day to protect your skin.

Night Use Only: Use retinol exclusively in your evening routine. Avoid daytime application.

Results Timeline: Visible improvements typically appear within 4-12 weeks of consistent use. Patience is key for optimal results.
How often should I use a Retinol serum?

Dermaworks’ high strength 2.5% Retinol Serum is a night serum. Retinol is photosensitive, meaning that sunlight impairs its effectiveness. Retinol does all its work while you are asleep, so we recommend applying to a clean, make-up free face before going to bed.

After cleansing, apply a few drops in to your palm and gently massage into the face, neck, décolletage and hands. Job done!

Retinol increases cell turnover. This may initially result in some flaking skin and/or slight redness. This is perfectly normal and should quickly return to normal after a few days.

If you are new to retinol and you find that your skin is a little sensitive, simply reduce the frequency of treatment to every two or three nights, gradually increasing to every night, once your skin has adjusted.

For best results, allow the serum to absorb then apply Dermaworks' Hyaluronic Acid Serum followed by your favourite moisturiser.
Is Retinol suitable for all skin types?

Our products are safe for all skin types, even the most sensitive, but we recommend you slowly build a regimen to ensure a positive reaction to retinol. We advise against using retinol on sore or broken skin.
When should I start using a Retinol serum?

NOW and until you’re 150! It’s never too early, nor too late to start using retinol. Treat your skin to retinol, every day and forever – it will love you for it!
What skincare can you use a Retinol serum alongside?

Here are some key skincare products that can be used alongside a retinol serum:

Cleanser: Begin your skincare routine with a gentle cleanser that suits your skin type. Look for a cleanser that doesn't strip the skin of its natural oils and maintains the skin's moisture balance. Avoid harsh exfoliants or abrasive scrubs that may cause additional irritation when used with retinol.

Moisturiser: Retinol can sometimes cause dryness and skin sensitivity, so it's crucial to follow up with a moisturiser to replenish hydration and maintain a healthy skin barrier. Look for a moisturiser that is suitable for your skin type and provides adequate moisture without clogging pores.

Sunscreen: Sun protection is essential when using retinol because retinol increases the skin's sensitivity to sunlight. Ensure you apply a broad-spectrum sunscreen with an SPF of 30 or higher during the day, even if you're not spending much time outdoors. This will help protect your skin from harmful UVA and UVB rays and prevent potential sun damage.

Hyaluronic Acid: Hyaluronic acid can be used alongside retinol to enhance hydration. As retinol can cause dryness, hyaluronic acid's ability to attract and retain moisture will help counterbalance that effect, keeping the skin plump and hydrated.

Vitamin C: Incorporating a vitamin C serum into your routine alongside retinol can provide additional antioxidant benefits. Vitamin C helps protect the skin from free radicals, brightens the complexion, and supports collagen production. Use vitamin C in the morning, as its antioxidant properties are particularly beneficial during the day.

Gentle Exfoliants: Retinol itself is an exfoliant, so it's generally advisable to avoid using additional harsh exfoliants, such as physical scrubs or strong chemical exfoliants, while using retinol. However, mild exfoliants like alpha hydroxy acids (AHAs) or beta hydroxy acids (BHAs) can be used sparingly and at separate times from retinol to avoid over-exfoliating the skin.
Can Retinol be used to treat acne?

Yes, retinol can be effective in treating acne. Retinol is a derivative of vitamin A and belongs to a class of compounds known as retinoids. It is commonly used in skincare products for its ability to promote cell turnover, prevent the formation of comedones (clogged pores), and reduce inflammation. These properties make retinol a valuable component in the treatment of acne.

Here's how retinol can help with acne:

Promoting Cell Turnover: Retinol speeds up the natural exfoliation process of the skin, helping to remove dead skin cells that can contribute to clogged pores and acne.

Preventing Comedone Formation: Retinol helps prevent the formation of comedones, which are the primary lesions in acne. By reducing the formation of these clogged pores, retinol can help prevent the development of new acne lesions.

Anti-inflammatory Effects: Retinol has anti-inflammatory properties that can help reduce redness and swelling associated with acne lesions.

Save with our skincare bundles

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Face cloth, retinol serum, and face cream displayed together for a complete skincare routine.
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Women's Anti-Aging Skincare Bundle: Face Cloths, Serum & Moisturiser

Women's Anti-Aging Skincare Bundle: Face Cloths, Serum & Moisturiser
£ 41.50 GBP
£ 41.50 GBP £ 46.40 GBP

Expertly Combining Science and Nature since 2013

At Dermaworks, we bring together the best of science and nature to deliver effective, cruelty-free skincare and beauty that truly performs.

Trusted by thousands, our expert formulations target aging, hydration, and brightening using only high-quality, ethically sourced ingredients.


Featured in Vogue, Tatler, and Woman & Home.

Discover beauty that works — because you deserve nothing less.

Why Choose Dermaworks