
What's the Best Age to Start Using Retinol? A Decade-by-Decade Guide
and how to start the right way.
- Weeks 1–2Your skin adjusts
- Weeks 2–4Smoother texture
- Weeks 6–8Fine lines start to soften
- Month 3+Firmer, clearer skin
★★★★★ 4.6 from 97 reviews · 60-day money-back guarantee*
Written by Jasmin | Years of skincare know-how & all things Dermaworks
5 min read
Quick answer
There's no single best age: retinol works at any age. Most people get the most from starting in their mid-20s to 30s, as collagen naturally begins to slow, but it delivers visible results in your 40s, 50s, 60s and beyond too. Whatever your age, start with a few drops 2–3 nights a week, follow with hyaluronic acid and moisturiser, and wear SPF every morning.
Here's the good news: it's never too early or too late to start retinol. Most people get the most from starting in their mid-20s to 30s, just as collagen naturally begins to slow, but retinol delivers visible results at any age, from your 20s to your 60s and beyond. Start earlier and you get ahead of fine lines; start later and you tackle the lines, wrinkles, texture and firmness that are already there.
Retinol is the anti-ageing powerhouse: a form of vitamin A that boosts collagen and speeds up your skin's renewal, for smoother, firmer, younger-looking skin. Our 2.5% Retinol Night Serum is clinically proven to increase collagen production by up to 5x. Here's exactly what retinol can do for you, decade by decade, and how to start the right way.
The best age to start retinol, decade by decade
Whatever your age, the way you start is the same: a few drops at night, 2–3 nights a week, building up to every night. What changes is what retinol does for you.
In your 20s: get ahead of the first lines
You may not see wrinkles yet, but this is when collagen naturally starts to slow. Starting retinol now keeps skin smooth, clear and even-toned, helps keep pores clear and breakouts in check, and gets you ahead of the first fine lines before they settle in.
In your 30s: the sweet spot to start
The first fine lines around your eyes and forehead start to show, and skin can look a little duller and slower to bounce back. Retinol boosts collagen to soften those first lines, refines texture and brings back a fresher, brighter look. For many people, this is the perfect time to start.
In your 40s: where retinol really earns its place
Lines deepen, skin loses some of its firmness and dark spots become more noticeable. Retinol works every night to smooth the look of lines and wrinkles, firm the skin and fade sun spots for a more even tone. Pair it with hyaluronic acid to keep your skin plump and comfortable.
In your 50s, 60s and beyond: it's never too late
Retinol keeps delivering results whenever you start. It helps smooth the look of deeper lines, improve texture and firmness and even out age spots, so your skin looks visibly fresher and more radiant. As skin naturally gets drier with age, always follow with hyaluronic acid and a nourishing moisturiser.

Real results
★★★★★“I love this product, it is helping to smooth out my wrinkles already. I have just ordered another bottle.”
Shirley Bagshaw, Dermaworks customer
★★★★★ 4.6 from 97 reviews
How to start retinol at any age
Start 2–3 nights a week. Build up to every night as your skin adjusts.
Use a few drops on clean, dry skin. Smooth our 2.5% Retinol Night Serum over your face, neck and décolletage, avoiding the skin right around your eyes and lips.
Hydrate straight after. Follow with our Hyaluronic Acid Serum and our Pure Radiance Face Cream or Men's Daily Moisturiser.
Wear SPF every morning. Retinol makes skin more sensitive to the sun, and SPF protects your results.
Give it 6–8 weeks. Skin feels smoother within 2–4 weeks, and fine lines start to look softer from around weeks 6–8.
What strength of retinol should you start with?
You might read that you should start with a weak retinol in your 20s and work up to a stronger one later. In reality, the formula matters as much as the number. A low-strength retinol can be gentle, but it can also take a long time to show results. Ours is a high-strength 2.5%, balanced with botanical hyaluronic acid, organic aloe vera and vitamin E, so it's powerful enough to deliver visible results, yet comfortable enough for beginners when you start slowly.
That's why the same serum works whether you're 25 or 65: what changes is how quickly you build up, not the bottle you buy. A little dryness or flaking in the first couple of weeks is normal; if it lasts, drop back to every second or third night.
Real results
Real results from real customers
I love the natural ingredients. I would give this serum 10/10 and would highly recommend to all skin types.
HanaVerified buyer
I absolutely love this product. I’ve been using it every 3 days in the evening for the last month and the difference it’s made to my skin is crazy.
Max’s LookVerified buyer
Great product. It's has been only 2 weeks but already seen improvement on my skin... definitely clearer.
M. Alves De AlmadaVerified buyer
Who should use retinol?
Whatever your age, retinol really earns its place if you're noticing:
- Fine lines and wrinkles, or skin that's lost some of its firmness.
- Rough or uneven texture, or skin that looks dull and tired.
- Enlarged pores, blackheads or breakouts.
- Dark spots, sun spots or post-blemish marks.
- Or nothing yet, and you want to keep it that way.
Who should wait? Avoid retinol if you're pregnant or breastfeeding; our Hyaluronic Acid Serum and 20% Vitamin C Serum are great alternatives in the meantime. If you have very sensitive skin or a skin condition such as eczema or rosacea, start very slowly and try it on a small area first.
Why choose Dermaworks Retinol Serum?
Because it's made to REALLY work, at any age. Our 2.5% Retinol Night Serum is clinically proven to increase collagen production by up to 5x, and every ingredient has a purpose: hyaluronic acid to hydrate, aloe vera to soothe and vitamin E to protect. We've formulated our own skincare since 2014, our customers rate our retinol 4.6 out of 5, and it's £14.95 with our 60-day money-back guarantee. Shopping for him? Our Men's 2.5% Retinol Night Serum is the same high-strength formula.
For the complete routine, our 3 Serum Set adds our 20% Vitamin C Serum for the morning and Hyaluronic Acid Serum for both, for £34.95, saving you £9.90.
FAQs
Your questions, answered
Can you start retinol in your 20s?
Is it too late to start retinol in your 50s or 60s?
What strength of retinol should a beginner use?
Can I use retinol if I'm pregnant or breastfeeding?
It's never too late
Smoother, firmer skin,at any age.
Made by us, backed by our 60-day money-back guarantee.
5x award-winning · 100,000+ sold · Trusted since 2014
- Mix & match and save up to 15%
- Love it or your money back · 60 days*
*Conditions apply. See our money-back guarantee


